| 10. Jornada | 03.10.2021 | Slovan Bratislava | - | FK Pohronie | 5:1 | ||||
| 11. Jornada | 16.10.2021 | FK Pohronie | - | MFK Ružomberok | 2:2 | ||||
| 12. Jornada | 23.10.2021 | FK Pohronie | - | Spartak Trnava | 0:2 | ||||
| 15. Jornada | 20.11.2021 | ŠKF Sereď | - | FK Pohronie | 3:1 |  |
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| 16. Jornada | 27.11.2021 | FK Pohronie | - | Zlaté Moravce | 0:2 | ||||
| 17. Jornada | 04.12.2021 | FC DAC 1904 | - | FK Pohronie | 2:0 | ||||
| 18. Jornada | 11.12.2021 | FK Pohronie | - | FK Senica | 0:1 | |
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| 19. Jornada | 18.12.2021 | FK Pohronie | - | Tatran Liptovský Mikuláš | 2:2 |
Eslovaquia