| 1. Jornada | 24.10.2020 | San Francisco FC | - | Atlético Chiriquí | 1:1 | ||||
| 2. Jornada | 31.10.2020 | Plaza Amador | - | San Francisco FC | 0:0 | ||||
| 3. Jornada | 09.11.2020 | San Francisco FC | - | Alianza | 0:0 | ||||
| 4. Jornada | 14.11.2020 | UD Universitario | - | San Francisco FC | 0:1 | ||||
| 5. Jornada | 18.11.2020 | Sporting San Miguelito | - | San Francisco FC | 1:2 | ||||
| 8. Jornada | 28.11.2020 | San Francisco FC | - | Árabe Unido | 3:0 |  |
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| 6. Jornada | 02.12.2020 | San Francisco FC | - | Independiente de La Chorrera | 1:1 | ||||
| 7. Jornada | 04.12.2020 | Tauro FC | - | San Francisco FC | 1:0 | ||||
| 9. Jornada | 07.12.2020 | San Francisco FC | - | Costa del Este FC | 0:0 |
Panamá