| 5. Jornada | 06.02.2022 | Platense Zacatecoluca | - | AD Chalatenango | 1:1 |  |
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| 6. Jornada | 10.02.2022 | AD Chalatenango | - | Once Municipal | 1:0 | |
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| 7. Jornada | 13.02.2022 | CD Águila | - | AD Chalatenango | 0:1 | ||||
| 8. Jornada | 20.02.2022 | AD Chalatenango | - | Jocoro FC | 1:0 | ||||
| 9. Jornada | 23.02.2022 | FAS | - | AD Chalatenango | 1:3 | ||||
| 10. Jornada | 27.02.2022 | AD Chalatenango | - | Santa Tecla FC | 1:0 | |
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| 11. Jornada | 06.03.2022 | Municipal Limeño | - | AD Chalatenango | 0:1 | ||||
| 12. Jornada | 12.03.2022 | Atlético Marte | - | AD Chalatenango | 4:2 | ||||
| 13. Jornada | 20.03.2022 | AD Chalatenango | - | Isidro Metapán | 1:1 | |
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| 22. Jornada | 07.05.2022 | AD Chalatenango | - | Municipal Limeño | 0:0 |
El Salvador