| 1. Jornada | 01.08.2021 | Alianza | - | Municipal Limeño | 4:1 | ||||
| 2. Jornada | 08.08.2021 | Municipal Limeño | - | Luis Ángel Firpo | 1:1 | ||||
| 3. Jornada | 11.08.2021 | Once Municipal | - | Municipal Limeño | 4:1 | ||||
| 4. Jornada | 15.08.2021 | Municipal Limeño | - | FAS | 0:3 | ||||
| 5. Jornada | 22.08.2021 | Isidro Metapán | - | Municipal Limeño | 1:0 | ||||
| 6. Jornada | 25.08.2021 | Municipal Limeño | - | Atlético Marte | 1:2 | ||||
| 7. Jornada | 29.08.2021 | Santa Tecla FC | - | Municipal Limeño | 1:1 | ||||
| 8. Jornada | 12.09.2021 | Municipal Limeño | - | CD Águila | 1:0 | ||||
| 9. Jornada | 15.09.2021 | Jocoro FC | - | Municipal Limeño | 3:1 | ||||
| 11. Jornada | 26.09.2021 | Municipal Limeño | - | Platense Zacatecoluca | 0:1 | ||||
| 17. Jornada | 02.11.2021 | Atlético Marte | - | Municipal Limeño | 2:0 | ||||
| 18. Jornada | 07.11.2021 | Municipal Limeño | - | Santa Tecla FC | 1:1 | ||||
| 19. Jornada | 14.11.2021 | CD Águila | - | Municipal Limeño | 2:1 | ||||
| 20. Jornada | 17.11.2021 | Municipal Limeño | - | Jocoro FC | 0:0 | ||||
| 21. Jornada | 21.11.2021 | Municipal Limeño | - | AD Chalatenango | 0:3 |
El Salvador