| 1. Jornada | 14.08.2011 | River Plate | - | Nacional | 3:3 | ||||
| 2. Jornada | 21.08.2011 | Liverpool | - | River Plate | 1:2 | ||||
| 3. Jornada | 27.08.2011 | River Plate | - | Rentistas | 2:0 |  |
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| 4. Jornada | 04.09.2011 | Montevideo Wanderers | - | River Plate | 0:3 | ||||
| 5. Jornada | 11.09.2011 | River Plate | - | Rampla Juniors | 2:1 | ||||
| 6. Jornada | 18.09.2011 | Cerrito | - | River Plate | 0:0 | ||||
| 7. Jornada | 24.09.2011 | River Plate | - | Peñarol | 0:4 |  |
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| 8. Jornada | 02.10.2011 | CA Cerro | - | River Plate | 2:0 | ||||
| 9. Jornada | 09.10.2011 | River Plate | - | Cerro Largo | 2:1 | |
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| 10. Jornada | 15.10.2011 | Fénix | - | River Plate | 1:2 | ||||
| 11. Jornada | 06.11.2011 | River Plate | - | Bella Vista | 1:2 | |
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| 12. Jornada | 12.11.2011 | Danubio | - | River Plate | 0:0 | ||||
| 15. Jornada | 02.12.2011 | Defensor Sporting | - | River Plate | 0:2 |
Uruguay