| 5. Jornada | 04.02.2022 | Jocoro FC | - | Municipal Limeño | 3:0 | ||||
| 6. Jornada | 09.02.2022 | Municipal Limeño | - | FAS | 1:1 |  |
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| 7. Jornada | 13.02.2022 | Santa Tecla FC | - | Municipal Limeño | 1:1 | ||||
| 8. Jornada | 20.02.2022 | Municipal Limeño | - | Alianza | 0:0 | |
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| 9. Jornada | 23.02.2022 | Municipal Limeño | - | Atlético Marte | 2:0 | ||||
| 10. Jornada | 27.02.2022 | Isidro Metapán | - | Municipal Limeño | 2:0 | |
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| 12. Jornada | 13.03.2022 | Municipal Limeño | - | Luis Ángel Firpo | 3:2 | ||||
| 13. Jornada | 20.03.2022 | Platense Zacatecoluca | - | Municipal Limeño | 1:0 | ||||
| 17. Jornada | 13.04.2022 | FAS | - | Municipal Limeño | 1:1 | ||||
| 18. Jornada | 17.04.2022 | Municipal Limeño | - | Santa Tecla FC | 2:0 | ||||
| 21. Jornada | 01.05.2022 | Municipal Limeño | - | Isidro Metapán | 1:0 |  |
El Salvador