| 1. Jornada | 27.09.2020 | Lobos UPNFM | - | Motagua | 2:3 | ||||
| 2. Jornada | 07.10.2020 | Real Sociedad | - | Lobos UPNFM | 2:3 |  |
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| 3. Jornada | 11.10.2020 | Olimpia | - | Lobos UPNFM | 3:1 | ||||
| 5. Jornada | 19.10.2020 | Honduras Progreso | - | Lobos UPNFM | 2:3 | ||||
| 7. Jornada | 24.10.2020 | Lobos UPNFM | - | Real Sociedad | 1:1 | ||||
| 8. Jornada | 29.10.2020 | Lobos UPNFM | - | Olimpia | 1:1 | ||||
| 9. Jornada | 01.11.2020 | Real de Minas | - | Lobos UPNFM | 1:1 | ||||
| 13. Jornada | 15.11.2020 | Lobos UPNFM | - | Real España | 1:1 |  |
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| 11. Jornada | 26.11.2020 | Lobos UPNFM | - | Marathón | 0:2 | ||||
| 12. Jornada | 30.11.2020 | Platense | - | Lobos UPNFM | 1:1 | ||||
| 6. Jornada | 06.12.2020 | Motagua | - | Lobos UPNFM | 0:1 | ||||
| 14. Jornada | 12.12.2020 | Vida | - | Lobos UPNFM | 0:3 |
Honduras