| 2. Jornada | 13.03.2021 | Jorge Wilstermann | - | Nacional Potosí | 1:2 | ||||
| 3. Jornada | 04.04.2021 | Oriente Petrolero | - | Jorge Wilstermann | 4:2 | ||||
| 16. Jornada | 20.08.2021 | Jorge Wilstermann | - | Real Santa Cruz | 5:1 | ||||
| 17. Jornada | 22.08.2021 | Nacional Potosí | - | Jorge Wilstermann | 0:1 | ||||
| 18. Jornada | 12.09.2021 | Jorge Wilstermann | - | Oriente Petrolero | 0:1 | ||||
| 19. Jornada | 19.09.2021 | The Strongest | - | Jorge Wilstermann | 3:1 | ||||
| 22. Jornada | 20.10.2021 | Always Ready | - | Jorge Wilstermann | 0:0 | ||||
| 26. Jornada | 22.11.2021 | Blooming | - | Jorge Wilstermann | 2:2 |  |
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| 27. Jornada | 28.11.2021 | Jorge Wilstermann | - | Bolívar | 1:0 |
Bolivia