| 1. Jornada | 29.08.2021 | Beitar Jerusalem | - | Hapoel Be'er Sheva | 0:2 | ||||
| 2. Jornada | 12.09.2021 | Hapoel Be'er Sheva | - | Hapoel Hadera | 2:2 | ||||
| 4. Jornada | 25.09.2021 | Hapoel Be'er Sheva | - | Maccabi Tel Aviv | 2:0 |  |
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| 9. Jornada | 06.11.2021 | Hapoel Be'er Sheva | - | FC Ashdod | 1:1 | ||||
| 15. Jornada | 26.12.2021 | Hapoel Hadera | - | Hapoel Be'er Sheva | 1:2 | ||||
| 16. Jornada | 02.01.2022 | Hapoel Be'er Sheva | - | Bnei Sachnin FC | 3:0 | ||||
| 19. Jornada | 23.01.2022 | Maccabi Petach-Tikva | - | Hapoel Be'er Sheva | 0:1 | |
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| 20. Jornada | 29.01.2022 | Hapoel Jerusalem | - | Hapoel Be'er Sheva | 0:1 | ||||
| 25. Jornada | 06.03.2022 | Hapoel Be'er Sheva | - | Hapoel Haifa | 3:1 |  |
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| 26. Jornada | 13.03.2022 | Hapoel Nof HaGalil | - | Hapoel Be'er Sheva | 0:2 |
Israel