| 4. Jornada | 17.10.2021 | FC Santa Coloma | - | FC Ordino | 3:2 | ||||
| 5. Jornada | 24.10.2021 | FC Santa Coloma | - | UE Sant Julià | 1:3 | ||||
| 6. Jornada | 31.10.2021 | Inter Club d'Escaldes | - | FC Santa Coloma | 1:1 |  |
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| 7. Jornada | 07.11.2021 | FC Santa Coloma | - | Atlétic Escaldes | 1:3 | |
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| 9. Jornada | 28.11.2021 | UE Engordany | - | FC Santa Coloma | 2:4 | |
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| 10. Jornada | 19.12.2021 | FC Santa Coloma | - | CE Carroi | 3:0 | ||||
| 12. Jornada | 19.01.2022 | UE Sant Julià | - | FC Santa Coloma | 0:0 | |
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| 11. Jornada | 02.02.2022 | FC Ordino | - | FC Santa Coloma | 0:0 | |
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| 14. Jornada | 06.02.2022 | Atlétic Escaldes | - | FC Santa Coloma | 2:1 | ||||
| 16. Jornada | 20.02.2022 | FC Santa Coloma | - | UE Engordany | 1:1 | ||||
| 17. Jornada | 27.02.2022 | CE Carroi | - | FC Santa Coloma | 0:5 | |
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| 18. Jornada | 06.03.2022 | FC Santa Coloma | - | FC Ordino | 2:1 | |
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| 19. Jornada | 13.03.2022 | FC Santa Coloma | - | UE Sant Julià | 2:0 | ||||
| 20. Jornada | 20.03.2022 | Inter Club d'Escaldes | - | FC Santa Coloma | 1:2 | ||||
| 21. Jornada | 03.04.2022 | FC Santa Coloma | - | Atlétic Escaldes | 1:1 |
Portugal