| 6. Jornada | 31.07.2022 | Santos Laguna [Sub 18] | - | Atlas Guadalajara [Sub 18] | 2:0 | ||||
| 1. Jornada | 03.08.2022 | Santos Laguna [Sub 18] | - | CF Monterrey [Sub 18] | 5:2 | ||||
| 7. Jornada | 06.08.2022 | Santos Laguna [Sub 18] | - | Cruz Azul [Sub 18] | 2:1 | ||||
| 9. Jornada | 18.08.2022 | Santos Laguna [Sub 18] | - | Club León [Sub 18] | 3:2 | ||||
| 10. Jornada | 21.08.2022 | Pumas UNAM [Sub 18] | - | Santos Laguna [Sub 18] | 2:0 | ||||
| 11. Jornada | 28.08.2022 | Santos Laguna [Sub 18] | - | Atlético San Luis [Sub 18] | 0:1 |
México