| 1. Jornada | 24.07.2021 | KV Kortrijk | - | RFC Seraing | 2:0 | ||||
| 13. Jornada | 30.10.2021 | K Beerschot VA | - | RFC Seraing | 3:0 | ||||
| 14. Jornada | 07.11.2021 | RFC Seraing | - | Gante | 0:0 | ||||
| 15. Jornada | 20.11.2021 | Oud-Heverlee Leuven | - | RFC Seraing | 1:3 |  |
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| 17. Jornada | 04.12.2021 | Club Brugge KV | - | RFC Seraing | 3:2 | ||||
| 18. Jornada | 11.12.2021 | RFC Seraing | - | RSC Anderlecht | 0:5 | ||||
| 19. Jornada | 14.12.2021 | Cercle Brugge | - | RFC Seraing | 2:0 | ||||
| 21. Jornada | 27.12.2021 | KV Mechelen | - | RFC Seraing | 2:0 | ||||
| 22. Jornada | 18.01.2022 | RFC Seraing | - | Union Saint-Gilloise | 0:4 | |
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| 24. Jornada | 26.01.2022 | RFC Seraing | - | K Beerschot VA | 2:1 | ||||
| 25. Jornada | 29.01.2022 | RFC Seraing | - | KAS Eupen | 0:0 | ||||
| 26. Jornada | 04.02.2022 | Sporting Charleroi | - | RFC Seraing | 2:0 | ||||
| 30. Jornada | 05.03.2022 | RFC Seraing | - | Club Brugge KV | 0:5 | |
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| 31. Jornada | 13.03.2022 | Standard Liège | - | RFC Seraing | 0:1 | ||||
| 32. Jornada | 19.03.2022 | RFC Seraing | - | Oud-Heverlee Leuven | 1:1 |
Bélgica
Marruecos