| 15. Jornada | 19.11.2021 | MFK Ružomberok | - | AS Trenčín | 3:0 |  |
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| 16. Jornada | 28.11.2021 | Spartak Trnava | - | MFK Ružomberok | 0:3 | ||||
| 17. Jornada | 04.12.2021 | MFK Zemplín Michalovce | - | MFK Ružomberok | 0:3 | |
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| 18. Jornada | 11.12.2021 | MFK Ružomberok | - | Zlaté Moravce | 1:1 | |
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| 19. Jornada | 17.12.2021 | FC DAC 1904 | - | MFK Ružomberok | 0:0 |
Eslovaquia