| 2. Jornada | 31.07.2021 | Mazatlán FC [Sub 16] | - | Atlético San Luis [Sub 16] | 4:0 | ||||
| 13. Jornada | 16.10.2021 | Atlético San Luis [Sub 16] | - | UANL Tigres [Sub 16] | 0:2 | ||||
| 14. Jornada | 23.10.2021 | Club Necaxa [Sub 16] | - | Atlético San Luis [Sub 16] | 4:0 | ||||
| 15. Jornada | 30.10.2021 | Club León [Sub 16] | - | Atlético San Luis [Sub 16] | 2:1 | ||||
| 16. Jornada | 06.11.2021 | Atlético San Luis [Sub 16] | - | Mazatlán FC [Sub 16] | 1:2 | ||||
| 18. Jornada | 20.11.2021 | Atlético San Luis [Sub 16] | - | Atlas Guadalajara [Sub 16] | 2:1 |
México