| 4. Jornada | 04.10.2020 | Apollon Smyrnis | - | AE Lárissa | 1:0 | ||||
| 5. Jornada | 17.10.2020 | Aris Saloniki | - | Apollon Smyrnis | 1:0 | ||||
| 1. Jornada | 21.10.2020 | Apollon Smyrnis | - | PAS Giannina | 1:2 |  |
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| 2. Jornada | 03.11.2020 | Panathinaikos | - | Apollon Smyrnis | 1:0 | |
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| 8. Jornada | 08.11.2020 | Apollon Smyrnis | - | PAOK Saloniki | 1:3 | |
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| 9. Jornada | 21.11.2020 | Atromitos | - | Apollon Smyrnis | 2:2 | ||||
| 3. Jornada | 25.11.2020 | Asteras Tripolis | - | Apollon Smyrnis | 0:0 | ||||
| 10. Jornada | 30.11.2020 | Apollon Smyrnis | - | Volos NFC | 3:3 | ||||
| 11. Jornada | 06.12.2020 | OFI Heraklion | - | Apollon Smyrnis | 0:2 | |
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| 12. Jornada | 13.12.2020 | Apollon Smyrnis | - | AEK Athen | 3:4 |  |
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| 17. Jornada | 16.01.2021 | AE Lárissa | - | Apollon Smyrnis | 0:1 | ||||
| 20. Jornada | 31.01.2021 | Apollon Smyrnis | - | Olympiacos | 1:3 | |
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| 21. Jornada | 07.02.2021 | PAOK Saloniki | - | Apollon Smyrnis | 2:2 | |
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| 6. Jornada | 18.02.2021 | Apollon Smyrnis | - | Lamia | 0:1 |  |
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| 24. Jornada | 27.02.2021 | Apollon Smyrnis | - | OFI Heraklion | 2:1 | ||||
| 25. Jornada | 08.03.2021 | AEK Athen | - | Apollon Smyrnis | 2:0 | ||||
| 26. Jornada | 14.03.2021 | Apollon Smyrnis | - | Panetolikos | 1:0 |
Grecia