| 1. Jornada | 01.02.2025 | Atlético FC | - | Barranquilla FC | 1:2 |  |
 |
||
| 2. Jornada | 11.02.2025 | Barranquilla FC | - | Real Santander | 1:2 | |
|||
| 3. Jornada | 17.02.2025 | Patriotas FC | - | Barranquilla FC | 1:0 | ||||
| 4. Jornada | 24.02.2025 | Barranquilla FC | - | Leones FC | 2:3 | |
|||
| 6. Jornada | 09.03.2025 | Orsomarso SC | - | Barranquilla FC | 3:0 | ||||
| 7. Jornada | 18.03.2025 | Barranquilla FC | - | Jaguares de Córdoba | 0:1 | ||||
| 8. Jornada | 25.03.2025 | Internacional de Palmira | - | Barranquilla FC | 3:0 | ||||
| 9. Jornada | 29.03.2025 | Barranquilla FC | - | Real Cartagena | 2:2 | |
 |
||
| 12. Jornada | 17.04.2025 | Real Soacha Cundinamarca | - | Barranquilla FC | 2:0 | ||||
| 5. Jornada | 24.04.2025 | Barranquilla FC | - | Deportes Quindío | 1:1 | |
|||
| 13. Jornada | 28.04.2025 | Barranquilla FC | - | Atlético Huila | 0:0 | ||||
| 14. Jornada | 07.05.2025 | Real Cartagena | - | Barranquilla FC | 3:0 | ||||
| 15. Jornada | 11.05.2025 | Barranquilla FC | - | Boca Juniors de Cali | 0:0 | ||||
| 16. Jornada | 18.05.2025 | Tigres FC | - | Barranquilla FC | 1:1 | |
Colombia