| 1. Jornada | 28.08.2021 | Persipura Jayapura | - | Persita Tangerang | 1:2 | ||||
| 2. Jornada | 10.09.2021 | Persela Lamongan | - | Persipura Jayapura | 1:0 | ||||
| 3. Jornada | 19.09.2021 | Persipura Jayapura | - | Persija Jakarta | 0:0 | ||||
| 4. Jornada | 24.09.2021 | Persiraja Banda Aceh | - | Persipura Jayapura | 1:2 | ||||
| 5. Jornada | 29.09.2021 | Persipura Jayapura | - | Arema Cronus FC | 0:1 | ||||
| 6. Jornada | 03.10.2021 | Madura United | - | Persipura Jayapura | 2:2 | ||||
| 7. Jornada | 16.10.2021 | Persipura Jayapura | - | Persebaya Surabaya | 1:3 | ||||
| 8. Jornada | 21.10.2021 | Persik Kediri | - | Persipura Jayapura | 4:2 | ||||
| 11. Jornada | 05.11.2021 | Persipura Jayapura | - | Bali United | 0:1 |  |
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| 18. Jornada | 06.01.2022 | Persipura Jayapura | - | Persela Lamongan | 1:1 | ||||
| 26. Jornada | 18.02.2022 | Persipura Jayapura | - | Persib Bandung | 0:3 | ||||
| 27. Jornada | 24.02.2022 | Bali United | - | Persipura Jayapura | 4:1 | ||||
| 28. Jornada | 28.02.2022 | Persipura Jayapura | - | Borneo FC | 2:1 | ||||
| 29. Jornada | 05.03.2022 | Persikabo 1973 | - | Persipura Jayapura | 1:1 | ||||
| 30. Jornada | 10.03.2022 | Persipura Jayapura | - | PSM Makassar | 0:0 | ||||
| 32. Jornada | 20.03.2022 | Persipura Jayapura | - | PSS Sleman | 4:2 |
Indonesia