| 1. Jornada | 09.08.2021 | FC Utrecht (J) | - | MVV | 0:1 | ||||
| 2. Jornada | 13.08.2021 | MVV | - | De Graafschap | 1:3 | ||||
| 3. Jornada | 20.08.2021 | MVV | - | Helmond Sport | 3:2 | ||||
| 4. Jornada | 27.08.2021 | FC Volendam | - | MVV | 5:0 | ||||
| 5. Jornada | 05.09.2021 | MVV | - | Telstar | 3:0 | ||||
| 6. Jornada | 10.09.2021 | FC Emmen | - | MVV | 7:1 | ||||
| 7. Jornada | 17.09.2021 | MVV | - | FC Eindhoven | 1:0 | ||||
| 8. Jornada | 27.09.2021 | Jong Ajax | - | MVV | 3:1 | ||||
| 9. Jornada | 01.10.2021 | MVV | - | ADO Den Haag | 2:6 | ||||
| 10. Jornada | 09.10.2021 | VVV-Venlo | - | MVV | 2:0 | ||||
| 11. Jornada | 15.10.2021 | MVV | - | FC Dordrecht | 2:1 | ||||
| 12. Jornada | 22.10.2021 | NAC Breda | - | MVV | 3:0 |
Países Bajos