| 1. Jornada | 18.07.2016 | Santos Laguna | - | UANL Tigres | 0:0 | ||||
| 2. Jornada | 23.07.2016 | CD Veracruz | - | Santos Laguna | 2:0 | ||||
| 3. Jornada | 01.08.2016 | Santos Laguna | - | Monarcas Morelia | 2:4 | ||||
| 4. Jornada | 08.08.2016 | Puebla FC | - | Santos Laguna | 0:0 |  |
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| 6. Jornada | 21.08.2016 | Cruz Azul | - | Santos Laguna | 3:1 | ||||
| 8. Jornada | 11.09.2016 | Club Necaxa | - | Santos Laguna | 2:1 | ||||
| 16. Jornada | 07.11.2016 | Santos Laguna | - | Chiapas FC | 2:0 |  |
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| 17. Jornada | 20.11.2016 | Deportivo Toluca | - | Santos Laguna | 1:2 |
México