| 1. Jornada | 16.07.2021 | CFR Cluj | - | FC Universitatea Craiova | 3:2 | ||||
| 3. Jornada | 31.07.2021 | CFR Cluj | - | Chindia Târgoviște | 1:0 | ||||
| 4. Jornada | 06.08.2021 | CS Mioveni | - | CFR Cluj | 0:1 | ||||
| 6. Jornada | 21.08.2021 | Argeș Pitești | - | CFR Cluj | 0:1 | ||||
| 7. Jornada | 29.08.2021 | CFR Cluj | - | FCSB | 4:1 | ||||
| 8. Jornada | 11.09.2021 | FC Botoşani | - | CFR Cluj | 1:0 | ||||
| 9. Jornada | 20.09.2021 | CFR Cluj | - | CS Universitatea Craiova | 1:0 | ||||
| 10. Jornada | 26.09.2021 | UTA Arad | - | CFR Cluj | 0:1 | ||||
| 12. Jornada | 17.10.2021 | Rapid Bucureşti | - | CFR Cluj | 2:0 |  |
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| 15. Jornada | 07.11.2021 | Dinamo Bucureşti | - | CFR Cluj | 0:3 | ||||
| 16. Jornada | 20.11.2021 | FC Universitatea Craiova | - | CFR Cluj | 0:2 | ||||
| 17. Jornada | 29.11.2021 | CFR Cluj | - | Academica Clinceni | 2:0 |  |
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| 18. Jornada | 04.12.2021 | Chindia Târgoviște | - | CFR Cluj | 0:1 | |
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| 19. Jornada | 12.12.2021 | CFR Cluj | - | CS Mioveni | 1:0 | |
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| 20. Jornada | 16.12.2021 | Farul Constanța | - | CFR Cluj | 0:2 | |
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| 21. Jornada | 19.12.2021 | CFR Cluj | - | Argeș Pitești | 1:0 | ||||
| 22. Jornada | 23.01.2022 | FCSB | - | CFR Cluj | 3:3 | ||||
| 23. Jornada | 31.01.2022 | CFR Cluj | - | FC Botoşani | 1:1 |
Rumania