| 2. Jornada | 01.08.2010 | NK Osijek | - | Hajduk Split | 2:2 | ||||
| 3. Jornada | 06.08.2010 | NK Zagreb | - | NK Osijek | 0:0 | ||||
| 4. Jornada | 14.08.2010 | NK Osijek | - | Lokomotiva Zagreb | 0:0 | ||||
| 5. Jornada | 21.08.2010 | NK Istra 1961 | - | NK Osijek | 1:2 | ||||
| 9. Jornada | 25.09.2010 | NK Osijek | - | NK Zadar | 3:2 |  |
|||
| 10. Jornada | 02.10.2010 | RNK Split | - | NK Osijek | 1:0 | ||||
| 11. Jornada | 16.10.2010 | NK Osijek | - | Dinamo Zagreb | 1:3 | |
 |
||
| 12. Jornada | 23.10.2010 | HNK Rijeka | - | NK Osijek | 1:5 | |
|||
| 13. Jornada | 30.10.2010 | NK Osijek | - | NK Varaždin | 0:0 | ||||
| 14. Jornada | 06.11.2010 | NK Karlovac | - | NK Osijek | 1:0 | ||||
| 18. Jornada | 04.12.2010 | NK Osijek | - | NK Zagreb | 0:0 |
Croacia