| 6. Jornada | 11.09.2021 | St-Pryvé St-Hilaire | - | Guingamp (CFA) | 1:1 | ||||
| 9. Jornada | 09.10.2021 | Guingamp (CFA) | - | Caen (CFA) | 1:1 | ||||
| 13. Jornada | 26.01.2022 | Vannes OC | - | Guingamp (CFA) | 2:0 | ||||
| 19. Jornada | 19.02.2022 | Stade Plabennec | - | Guingamp (CFA) | 1:0 | ||||
| 23. Jornada | 26.03.2022 | Caen (CFA) | - | Guingamp (CFA) | 0:2 | ||||
| 24. Jornada | 09.04.2022 | AS Poissy | - | Guingamp (CFA) | 1:1 | ||||
| 25. Jornada | 16.04.2022 | Guingamp (CFA) | - | C'Chartres Football | 3:4 | ||||
| 26. Jornada | 23.04.2022 | Châteaubriant Voltigeurs | - | Guingamp (CFA) | 0:2 |  |
|||
| 27. Jornada | 30.04.2022 | Guingamp (CFA) | - | Vannes OC | 1:0 | |
|||
| 28. Jornada | 14.05.2022 | US Granvillaise | - | Guingamp (CFA) | 3:4 |  |
|||
| 29. Jornada | 21.05.2022 | Guingamp (CFA) | - | SO Romorantin | 1:2 | ||||
| 30. Jornada | 28.05.2022 | FC Rouen 1899 | - | Guingamp (CFA) | 2:1 |
Francia
R.D. Congo