| 1. Jornada | 23.08.1980 | TJ Tatran Prešov | - | TJ Slovan ChZJD Bratislava | 3:1 | ||||
| 10. Jornada | 26.10.1980 | TJ Tatran Prešov | - | TJ Baník Ostrava OKD | 0:1 | ||||
| 11. Jornada | 01.11.1980 | TJ Plastika Nitra | - | TJ Tatran Prešov | 0:0 | ||||
| 12. Jornada | 09.11.1980 | TJ Tatran Prešov | - | TJ Lokomotíva Košice | 2:1 | ||||
| 13. Jornada | 23.11.1980 | TJ Zbrojovka Brno | - | TJ Tatran Prešov | 2:2 | ||||
| 14. Jornada | 07.12.1980 | TJ Tatran Prešov | - | TJ Spartak TAZ Trnava | 4:1 |  |
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| 15. Jornada | 14.12.1980 | Sparta Praga | - | TJ Tatran Prešov | 4:0 | ||||
| 17. Jornada | 01.03.1981 | TJ Tatran Prešov | - | ASVŠ Dukla Banská Bystrica | 0:1 | ||||
| 18. Jornada | 08.03.1981 | Slavia Praga | - | TJ Tatran Prešov | 4:1 |  |
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| 19. Jornada | 15.03.1981 | TJ ZŤS Košice | - | TJ Tatran Prešov | 0:1 | |
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| 20. Jornada | 21.03.1981 | TJ Tatran Prešov | - | TJ Spartak ZVÚ Hradec Králové | 1:2 | ||||
| 23. Jornada | 19.04.1981 | TJ Internacionál Slovnaft Bratislava | - | TJ Tatran Prešov | 2:2 |
Eslovaquia