| 1. Jornada | 19.08.2022 | Birkirkara FC | - | Sirens FC | 2:0 |  |
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| 2. Jornada | 27.08.2022 | Sirens FC | - | Floriana FC | 2:2 | |
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| 3. Jornada | 03.09.2022 | Valletta FC | - | Sirens FC | 0:0 | ||||
| 4. Jornada | 10.09.2022 | Sirens FC | - | Hamrun Spartans | 0:2 | ||||
| 8. Jornada | 21.10.2022 | Sirens FC | - | Żebbuġ Rangers | 3:3 | |
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| 9. Jornada | 29.10.2022 | St. Luċija FC | - | Sirens FC | 0:0 | |
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| 11. Jornada | 13.11.2022 | Marsaxlokk FC | - | Sirens FC | 1:2 | ||||
| 12. Jornada | 03.12.2022 | Sirens FC | - | Hibernians FC | 0:1 | ||||
| 13. Jornada | 10.12.2022 | Pietá Hotspurs | - | Sirens FC | 0:1 |
Brasil