| 1. Jornada | 03.07.2020 | FC Sheriff | - | Speranţa Nisporeni | 2:0 | ||||
| 2. Jornada | 08.07.2020 | FC Sfîntul Gheorghe | - | FC Sheriff | 0:1 |  |
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| 3. Jornada | 11.07.2020 | FC Sheriff | - | FC Codru Lozova | 6:0 | |
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| 4. Jornada | 17.07.2020 | FC Sheriff | - | FC Zimbru | 2:0 | ||||
| 5. Jornada | 23.07.2020 | FC Milsami | - | FC Sheriff | 0:1 |  |
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| 6. Jornada | 26.07.2020 | FC Sheriff | - | Dinamo-Auto | 6:0 | ||||
| 7. Jornada | 01.08.2020 | FC Floreşti | - | FC Sheriff | 0:1 | ||||
| 8. Jornada | 05.08.2020 | FC Sheriff | - | CS Petrocub | 4:1 | ||||
| 9. Jornada | 12.09.2020 | Dacia Buiucani | - | FC Sheriff | 0:3 | |
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| 10. Jornada | 18.09.2020 | Speranţa Nisporeni | - | FC Sheriff | 1:2 | ||||
| 13. Jornada | 03.10.2020 | FC Zimbru | - | FC Sheriff | 0:4 | ||||
| 14. Jornada | 17.10.2020 | FC Sheriff | - | FC Milsami | 1:0 | |
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| 16. Jornada | 24.10.2020 | FC Sheriff | - | FC Floreşti | 5:0 | ||||
| 17. Jornada | 01.11.2020 | CS Petrocub | - | FC Sheriff | 1:0 | ||||
| 18. Jornada | 07.11.2020 | FC Sheriff | - | Dacia Buiucani | 0:0 | ||||
| 19. Jornada | 21.11.2020 | FC Sheriff | - | Speranţa Nisporeni | 3:0 | ||||
| 20. Jornada | 25.11.2020 | FC Sfîntul Gheorghe | - | FC Sheriff | 0:2 | ||||
| 21. Jornada | 28.11.2020 | FC Codru Lozova | - | FC Sheriff | 1:2 |
Colombia