| 2. Jornada | 16.07.2022 | Real Cartagena | - | Leones FC | 0:1 | ||||
| 3. Jornada | 22.07.2022 | Atlético Huila | - | Real Cartagena | 2:3 |  |
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| 4. Jornada | 29.07.2022 | Real Cartagena | - | Cúcuta Deportivo | 1:2 | ||||
| 5. Jornada | 04.08.2022 | Real Cartagena | - | Orsomarso SC | 0:1 | ||||
| 7. Jornada | 17.08.2022 | Real Cartagena | - | Real Santander | 2:2 |  |
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| 8. Jornada | 24.08.2022 | Boyacá Chicó | - | Real Cartagena | 4:0 |
Colombia