| 11. Jornada | 29.03.2025 | San Francisco FC | - | Alianza | 1:2 | ||||
| 12. Jornada | 05.04.2025 | San Francisco FC | - | Veraguas United | 4:0 | ||||
| 13. Jornada | 12.04.2025 | San Francisco FC | - | Herrera FC | 1:1 | ||||
| 14. Jornada | 26.04.2025 | San Francisco FC | - | Independiente de La Chorrera | 1:1 | ||||
| 15. Jornada | 03.05.2025 | UMECIT | - | San Francisco FC | 2:0 | ||||
| 16. Jornada | 10.05.2025 | San Francisco FC | - | UD Universitario | 3:0 |
Panamá