| 1. Jornada | 09.01.2021 | UANL Tigres [Sub 20] | - | Club León [Sub 20] | 6:0 | ||||
| 2. Jornada | 18.01.2021 | Club León [Sub 20] | - | CF Pachuca [Sub 20] | 0:3 | ||||
| 5. Jornada | 08.02.2021 | Club León [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 3:0 | ||||
| 6. Jornada | 13.02.2021 | Club Tijuana [Sub 20] | - | Club León [Sub 20] | 1:1 | ||||
| 7. Jornada | 21.02.2021 | Pumas UNAM [Sub 20] | - | Club León [Sub 20] | 1:4 | ||||
| 9. Jornada | 02.03.2021 | Club León [Sub 20] | - | Puebla FC [Sub 20] | 2:1 | ||||
| 10. Jornada | 06.03.2021 | CF América [Sub 20] | - | Club León [Sub 20] | 0:1 |  |
México