| 1. Jornada | 16.01.2022 | Alianza | - | Isidro Metapán | 0:2 | ||||
| 2. Jornada | 22.01.2022 | Jocoro FC | - | Alianza | 3:2 | ||||
| 3. Jornada | 27.01.2022 | Alianza | - | AD Chalatenango | 3:1 | ||||
| 5. Jornada | 06.02.2022 | Alianza | - | Luis Ángel Firpo | 0:0 | ||||
| 6. Jornada | 10.02.2022 | Santa Tecla FC | - | Alianza | 2:3 | ||||
| 14. Jornada | 25.03.2022 | AD Chalatenango | - | Alianza | 2:0 |
El Salvador