| 1. Jornada | 17.10.2021 | US Monastir | - | CS Chebba | 2:0 |  |
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| 2. Jornada | 24.10.2021 | AS Rejiche | - | US Monastir | 0:1 | ||||
| 4. Jornada | 04.11.2021 | AS Soliman | - | US Monastir | 0:0 | ||||
| 5. Jornada | 07.11.2021 | US Monastir | - | Club Africain | 0:0 | ||||
| 7. Jornada | 21.11.2021 | Espérance Zarzis | - | US Monastir | 0:1 | ||||
| 9. Jornada | 27.02.2022 | US Monastir | - | AS Rejiche | 0:1 | ||||
| 11. Jornada | 13.03.2022 | US Monastir | - | AS Soliman | 1:0 | |
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| 12. Jornada | 06.04.2022 | Club Africain | - | US Monastir | 2:0 | ||||
| 13. Jornada | 10.04.2022 | Olympique Béja | - | US Monastir | 0:0 | ||||
| 14. Jornada | 13.04.2022 | US Monastir | - | Espérance Zarzis | 0:1 |
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