 |
 |
|
|
| 29.01.2022 | 13:30 | Sint-Truidense VV | - | Royal Antwerp FC | 1:0 (0:0) | |
| 14:45 | KV Mechelen | - | Sporting Charleroi | 0:2 (0:0) | ||
| 16.02.2022 | 16:30 | Club Brugge KV | - | KAA Gent | 6:2 (0:0) | |
| 23.02.2022 | 18:30 | RSC Anderlecht | - | SV Zulte Waregem | 0:0 | |
| 09.04.2022 | 14:00 | Standard Liège | - | KRC Genk | 0:2 (0:0) | |
| 14:00 | Oud-Heverlee Leuven | - | Cercle Brugge | 4:2 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KRC Genk | 16 | 12 | 2 | 2 | 61:22 | 39 | 38 |
| 2 |
|
Club Brugge KV | 16 | 11 | 4 | 1 | 48:19 | 29 | 37 |
| 3 |
|
RSC Anderlecht | 15 | 8 | 5 | 2 | 36:22 | 14 | 29 |
| 4 |
|
Standard Liège | 16 | 8 | 2 | 6 | 25:20 | 5 | 26 |
| 5 |
|
KAA Gent | 16 | 8 | 2 | 6 | 37:34 | 3 | 26 |
| 6 |
|
SV Zulte Waregem | 16 | 6 | 7 | 3 | 26:19 | 7 | 25 |
| 7 |
|
Sporting Charleroi | 16 | 6 | 5 | 5 | 23:26 | -3 | 23 |
| 8 |
|
KV Mechelen | 16 | 6 | 2 | 8 | 31:33 | -2 | 20 |
| 9 |
|
Sint-Truidense VV | 16 | 5 | 5 | 6 | 17:23 | -6 | 20 |
| 10 |
|
Oud-Heverlee Leuven | 15 | 4 | 3 | 8 | 21:36 | -15 | 15 |
| 11 |
|
Royal Antwerp FC | 15 | 4 | 1 | 10 | 13:23 | -10 | 13 |
| 12 |
|
Cercle Brugge | 16 | 3 | 3 | 10 | 27:57 | -30 | 12 |
| 13 |
|
KVC Westerlo | 15 | 0 | 1 | 14 | 11:42 | -31 | 1 |
