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| 16.10.2021 | Sputnik Rechytsa | - | Neman Grodno | 0:3 | ||
| 12:00 | FK Isloch Minsk | - | FK Slutsk | 2:0 (1:0) | ||
| 14:00 | FK Smorgon | - | FK Vitebsk | 2:0 (1:0) | ||
| 16:00 | FK Slaviya Mozyr | - | BATE Borisov | 3:1 (0:0) | ||
| 17.10.2021 | 12:00 | FK Minsk | - | FK Gomel | 0:0 (0:0) | |
| 14:00 | Rukh Brest | - | Dinamo Minsk | 1:3 (1:2) | ||
| 16:00 | Energetik-BGU Minsk | - | Dinamo Brest | 0:0 (0:0) | ||
| 18:30 | Shakhter Soligorsk | - | Torpedo-BelAZ Zhodino | 3:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Shakhter Soligorsk | 26 | 22 | 2 | 2 | 56:15 | 41 | 68 |
| 2 |
|
BATE Borisov | 26 | 16 | 7 | 3 | 51:26 | 25 | 55 |
| 3 |
|
Dinamo Minsk | 26 | 17 | 3 | 6 | 49:19 | 30 | 54 |
| 4 |
|
Rukh Brest | 26 | 14 | 9 | 3 | 44:20 | 24 | 51 |
| 5 |
|
FK Gomel | 26 | 14 | 7 | 5 | 50:22 | 28 | 49 |
| 6 |
|
Dinamo Brest | 26 | 7 | 13 | 6 | 28:25 | 3 | 34 |
| 7 |
|
FK Vitebsk | 26 | 8 | 10 | 8 | 33:33 | 0 | 34 |
| 8 |
|
FK Isloch Minsk | 26 | 9 | 7 | 10 | 37:39 | -2 | 34 |
| 9 |
|
Torpedo-BelAZ Zhodino | 26 | 9 | 5 | 12 | 31:34 | -3 | 32 |
| 10 |
|
Neman Grodno | 26 | 8 | 6 | 12 | 32:30 | 2 | 30 |
| 11 |
|
FK Minsk | 26 | 7 | 8 | 11 | 30:44 | -14 | 29 |
| 12 |
|
Energetik-BGU Minsk | 26 | 7 | 8 | 11 | 28:34 | -6 | 29 |
| 13 |
|
FK Slutsk | 26 | 6 | 7 | 13 | 27:42 | -15 | 25 |
| 14 |
|
FK Slaviya Mozyr | 26 | 6 | 6 | 14 | 32:47 | -15 | 24 |
| 15 |
|
FK Smorgon | 26 | 3 | 7 | 16 | 23:63 | -40 | 16 |
| 16 |
|
Sputnik Rechytsa | 26 | 2 | 1 | 23 | 12:70 | -58 | 7 |
| CL Ronda previa | |
| ECL Ronda previa | |
| Permanencia | |
| Descenso |
