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| 06.08.2022 | 00:45 | Independiente Medellín | - | La Equidad | 1:1 (1:0) | |
| 02:50 | Patriotas FC | - | Cortuluá | 3:0 (3:0) | ||
| 21:00 | Envigado FC | - | Unión Magdalena | 1:2 (1:1) | ||
| 23:05 | Deportes Tolima | - | Jaguares de Córdoba | 2:2 (0:1) | ||
| 07.08.2022 | 01:10 | Alianza Petrolera | - | Atlético Nacional | 0:2 (0:0) | |
| 03:15 | Millonarios | - | Deportivo Cali | 4:2 (2:0) | ||
| 21:00 | Deportivo Pasto | - | Atlético Bucaramanga | 1:0 (1:0) | ||
| 08.08.2022 | 01:10 | Atlético Junior | - | Once Caldas | 1:2 (0:1) | |
| 03:15 | Deportivo Pereira | - | Santa Fe | 0:1 (0:0) | ||
| 10.08.2022 | 02:30 | América de Cali | - | Águilas Doradas | 2:0 (2:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Millonarios | 6 | 4 | 2 | 0 | 10:4 | 6 | 14 |
| 2 |
|
Unión Magdalena | 6 | 4 | 1 | 1 | 9:7 | 2 | 13 |
| 3 |
|
Once Caldas | 6 | 3 | 3 | 0 | 10:6 | 4 | 12 |
| 4 |
|
Deportivo Pasto | 6 | 3 | 1 | 2 | 9:6 | 3 | 10 |
| 5 |
|
América de Cali | 6 | 2 | 3 | 1 | 6:3 | 3 | 9 |
| 6 |
|
Deportivo Pereira | 6 | 3 | 0 | 3 | 7:6 | 1 | 9 |
|
Jaguares de Córdoba | 6 | 2 | 3 | 1 | 7:6 | 1 | 9 | |
| 8 |
|
Santa Fe | 6 | 2 | 3 | 1 | 7:7 | 0 | 9 |
| 9 |
|
Atlético Junior | 6 | 2 | 2 | 2 | 7:5 | 2 | 8 |
| 10 |
|
Atlético Nacional | 6 | 2 | 2 | 2 | 10:9 | 1 | 8 |
| 11 |
|
Águilas Doradas | 6 | 2 | 2 | 2 | 7:7 | 0 | 8 |
| 12 |
|
Patriotas FC | 6 | 2 | 1 | 3 | 7:7 | 0 | 7 |
| 13 |
|
Independiente Medellín | 6 | 1 | 4 | 1 | 6:6 | 0 | 7 |
| 14 |
|
Alianza Petrolera | 6 | 2 | 1 | 3 | 8:9 | -1 | 7 |
| 15 |
|
La Equidad | 6 | 1 | 4 | 1 | 8:10 | -2 | 7 |
| 16 |
|
Deportes Tolima | 6 | 1 | 3 | 2 | 9:9 | 0 | 6 |
| 17 |
|
Envigado FC | 6 | 1 | 2 | 3 | 6:9 | -3 | 5 |
| 18 |
|
Cortuluá | 6 | 1 | 2 | 3 | 3:7 | -4 | 5 |
| 19 |
|
Atlético Bucaramanga | 6 | 1 | 1 | 4 | 3:8 | -5 | 4 |
| 20 |
|
Deportivo Cali | 6 | 0 | 2 | 4 | 7:15 | -8 | 2 |
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