12.11.2021 16:00 Bibiani Gold Stars - Asante Kotoko 0:1 (0:0)
13.11.2021 16:00 Dreams FC - Accra Lions 3:1 (2:1)
19:00 Legon Cities - Great Olympics 0:1 (0:1)
14.11.2021 16:00 Bechem United - Elmina Sharks 2:0 (0:0)
16:00 Eleven Wonders - Medeama SC 0:0 (0:0)
16:00 Hearts of Oak - Aduana Stars 1:1 (1:0)
16:00 Karela FC - Berekum Chelsea 2:1 (1:1)
16:00 King Faisal - Ashanti Gold 2:0 (0:0)
16:00 Real Tamale United - WAFA 2:0 (1:0)
# Equipo P V E D Goles DG Pun.
1 Asante Kotoko, Ghana Asante Kotoko 3 3 0 0 6:1 5 9
  King Faisal, Ghana King Faisal 3 3 0 0 6:1 5 9
3 Great Olympics, Ghana Great Olympics 3 2 1 0 5:2 3 7
4 Bechem United, Ghana Bechem United 3 2 0 1 6:2 4 6
5 Dreams FC, Ghana Dreams FC 3 2 0 1 7:5 2 6
6 Karela FC, Ghana Karela FC 3 1 2 0 4:3 1 5
7 Real Tamale United, Ghana Real Tamale United 3 1 1 1 5:4 1 4
8 Legon Cities, Ghana Legon Cities 3 1 1 1 3:3 0 4
9 Bibiani Gold Stars, Ghana Bibiani Gold Stars 3 1 1 1 2:2 0 4
10 Ashanti Gold, Ghana Ashanti Gold 3 1 1 1 2:3 -1 4
11 Hearts of Oak, Ghana Hearts of Oak 3 0 3 0 2:2 0 3
12 Eleven Wonders, Ghana Eleven Wonders 3 0 2 1 0:1 -1 2
13 Aduana Stars, Ghana Aduana Stars 3 0 2 1 3:5 -2 2
14 Medeama SC, Ghana Medeama SC 3 0 2 1 1:5 -4 2
15 Berekum Chelsea, Ghana Berekum Chelsea 3 0 1 2 1:3 -2 1
16 WAFA, Ghana WAFA 3 0 1 2 1:4 -3 1
17 Accra Lions, Ghana Accra Lions 3 0 1 2 3:7 -4 1
18 Elmina Sharks, Ghana Elmina Sharks 3 0 1 2 2:6 -4 1
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