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| 11.12.2010 | 16:15 | Olympiacos Volou | - | Aris Saloniki | 1:1 (1:1) | |
| 18:30 | PAOK Saloniki | - | Iraklis Saloniki | 1:0 (1:0) | ||
| 12.12.2010 | 14:00 | Skoda Xanthi | - | AO Kavala | 1:1 (0:1) | |
| 14:00 | Panserraikos | - | Panionios GSS | 1:1 (1:0) | ||
| 14:00 | Ergotelis | - | AO Kerkyra | 3:0 (1:0) | ||
| 16:15 | Olympiacos | - | Atromitos | 2:1 (2:0) | ||
| 16:15 | AEK Athen | - | AE Lárissa | 4:0 (1:0) | ||
| 18:30 | Asteras Tripolis | - | Panathinaikos | 0:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiacos | 14 | 11 | 0 | 3 | 28:7 | 21 | 33 |
| 2 |
|
Panathinaikos | 14 | 9 | 4 | 1 | 23:10 | 13 | 31 |
| 3 |
|
AEK Athen | 14 | 7 | 2 | 5 | 23:14 | 9 | 23 |
| 4 |
|
PAOK Saloniki | 14 | 7 | 2 | 5 | 15:14 | 1 | 23 |
| 5 |
|
AO Kavala | 14 | 5 | 5 | 4 | 14:12 | 2 | 20 |
| 6 |
|
Aris Saloniki | 14 | 6 | 2 | 6 | 10:11 | -1 | 20 |
| 7 |
|
Skoda Xanthi | 14 | 4 | 6 | 4 | 13:16 | -3 | 18 |
| 8 |
|
Olympiacos Volou | 14 | 3 | 8 | 3 | 15:15 | 0 | 17 |
| 9 |
|
Ergotelis | 14 | 5 | 2 | 7 | 14:19 | -5 | 17 |
| 10 |
|
AO Kerkyra | 14 | 4 | 4 | 6 | 12:17 | -5 | 16 |
| 11 |
|
Iraklis Saloniki | 14 | 3 | 7 | 4 | 11:13 | -2 | 16 |
| 12 |
|
Atromitos | 14 | 3 | 6 | 5 | 13:17 | -4 | 15 |
| 13 |
|
Asteras Tripolis | 14 | 3 | 6 | 5 | 10:14 | -4 | 15 |
| 14 |
|
Panserraikos | 14 | 4 | 3 | 7 | 12:18 | -6 | 15 |
| 15 |
|
Panionios GSS | 14 | 4 | 2 | 8 | 9:18 | -9 | 14 |
| 16 |
|
AE Lárissa | 14 | 2 | 5 | 7 | 10:17 | -7 | 11 |
| Champions League | |
| Playoff | |
| Descenso |
