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| 15.04.2023 | 19:00 | Puebla FC | - | Cruz Azul | 0:1 (0:1) | |
| 19:00 | UANL Tigres | - | Mazatlán FC | 2:3 (1:2) | ||
| 19:30 | Club León | - | CF Monterrey | 5:2 (4:1) | ||
| 19:30 | Santos Laguna | - | Deportivo Guadalajara | 5:3 (4:1) | ||
| 19:30 | Deportivo Toluca | - | FC Juárez | 1:0 (0:0) | ||
| 19:30 | Club Necaxa | - | Pumas UNAM | 3:0 (1:0) | ||
| 21:45 | Club Tijuana | - | Atlético San Luis | 4:0 (3:0) | ||
| 21:45 | CF América | - | Gallos Blancos | 2:1 (0:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Necaxa | 13 | 11 | 1 | 1 | 33:8 | 25 | 34 |
| 2 |
|
CF América | 13 | 8 | 2 | 3 | 35:17 | 18 | 26 |
| 3 |
|
Pumas UNAM | 14 | 6 | 4 | 4 | 21:19 | 2 | 22 |
| 4 |
|
Cruz Azul | 13 | 5 | 5 | 3 | 23:21 | 2 | 20 |
| 5 |
|
CF Pachuca | 13 | 5 | 4 | 4 | 22:19 | 3 | 19 |
| 6 |
|
Puebla FC | 13 | 5 | 1 | 7 | 23:30 | -7 | 16 |
| 7 |
|
Deportivo Toluca | 13 | 4 | 2 | 7 | 11:17 | -6 | 14 |
| 8 |
|
Gallos Blancos | 14 | 3 | 2 | 9 | 10:19 | -9 | 11 |
| 9 |
|
FC Juárez | 14 | 1 | 3 | 10 | 10:38 | -28 | 6 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 13 | 10 | 1 | 2 | 32:17 | 15 | 31 |
| 2 |
|
Santos Laguna | 13 | 9 | 2 | 2 | 33:14 | 19 | 29 |
| 3 |
|
Club Tijuana | 13 | 7 | 5 | 1 | 38:12 | 26 | 26 |
| 4 |
|
Club León | 14 | 5 | 3 | 6 | 23:27 | -4 | 18 |
| 5 |
|
Deportivo Guadalajara | 14 | 5 | 3 | 6 | 22:32 | -10 | 18 |
| 6 |
|
Atlas Guadalajara | 13 | 5 | 2 | 6 | 23:23 | 0 | 17 |
| 7 |
|
UANL Tigres | 14 | 3 | 4 | 7 | 29:34 | -5 | 13 |
| 8 |
|
Mazatlán FC | 13 | 2 | 2 | 9 | 11:35 | -24 | 8 |
| 9 |
|
Atlético San Luis | 13 | 1 | 4 | 8 | 14:31 | -17 | 7 |
| Playoff | |
| Playoff |
