 |
 |
|
|
| 10.11.2021 | 00:00 | Atlético Morelia | - | Coyotes de Tlaxcala | 1:3 (0:1) | |
| 02:05 | Cancún FC | - | Alebrijes de Oaxaca | 1:2 (0:1) | ||
| 04:05 | Dorados de Sinaloa | - | TM Fútbol Club | 0:3 (0:3) | ||
| 11.11.2021 | 00:00 | Mineros de Zacatecas | - | Atlante | 0:3 (0:1) | |
| 02:05 | Pumas Tabasco | - | Tepatitlán | 1:1 (0:0) | ||
| 04:05 | Correcaminos UAT | - | CF Monterrey II | 2:1 (1:0) | ||
| 12.11.2021 | 02:00 | Tapatío | - | Club Celaya | 1:1 (1:0) | |
| 14.11.2021 | 19:00 | Leones Negros | - | Cimarrones de Sonora | 3:2 (3:2) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Dorados de Sinaloa | 15 | 10 | 4 | 1 | 33:13 | 20 | 34 |
| 2 |
|
Atlante | 15 | 9 | 4 | 2 | 22:8 | 14 | 31 |
| 3 |
|
Leones Negros | 15 | 7 | 4 | 4 | 20:16 | 4 | 25 |
| 4 |
|
Atlético Morelia | 15 | 7 | 4 | 4 | 21:18 | 3 | 25 |
| 5 |
|
Club Celaya | 15 | 6 | 4 | 5 | 17:15 | 2 | 22 |
| 6 |
|
Pumas Tabasco | 15 | 5 | 7 | 3 | 15:14 | 1 | 22 |
| 7 |
|
TM Fútbol Club | 15 | 4 | 9 | 2 | 22:17 | 5 | 21 |
| 8 |
|
Cimarrones de Sonora | 15 | 6 | 3 | 6 | 22:21 | 1 | 21 |
| 9 |
|
Coyotes de Tlaxcala | 15 | 4 | 6 | 5 | 15:18 | -3 | 18 |
| 10 |
|
Venados FC | 15 | 5 | 3 | 7 | 14:19 | -5 | 18 |
| 11 |
|
CF Monterrey II | 15 | 4 | 5 | 6 | 16:17 | -1 | 17 |
| 12 |
|
Alebrijes de Oaxaca | 16 | 3 | 7 | 6 | 14:17 | -3 | 16 |
| 13 |
|
Mineros de Zacatecas | 15 | 5 | 1 | 9 | 22:28 | -6 | 16 |
| 14 |
|
Correcaminos UAT | 15 | 4 | 4 | 7 | 18:27 | -9 | 16 |
| 15 |
|
Tepatitlán | 15 | 3 | 6 | 6 | 15:19 | -4 | 15 |
| 16 |
|
Tapatío | 15 | 3 | 5 | 7 | 11:24 | -13 | 14 |
| 17 |
|
Cancún FC | 15 | 3 | 4 | 8 | 13:19 | -6 | 13 |
| Playoff | |
| Playoff |
