 |
 |
|
|
| 03.08.2022 | 03:00 | Deportivo Toluca | - | Puebla FC | 1:1 (0:1) | |
| 04.08.2022 | 03:00 | FC Juárez | - | Atlético San Luis | 1:1 (0:1) | |
| 24.08.2022 | 02:05 | Deportivo Guadalajara | - | CF Monterrey | 1:0 (0:0) | |
| 04:05 | Gallos Blancos | - | CF América | 0:1 (0:0) | ||
| 25.08.2022 | 04:05 | Pumas UNAM | - | UANL Tigres | 1:1 (0:0) | |
| 26.08.2022 | 02:05 | CF Pachuca | - | Atlas Guadalajara | 3:1 (0:0) | |
| 04:05 | Club Tijuana | - | Santos Laguna | 0:2 (0:0) | ||
| 16.09.2022 | 02:00 | Cruz Azul | - | Club León | 2:1 (0:0) | |
| 24.09.2022 | 02:00 | Club Necaxa | - | Mazatlán FC | 2:2 (1:2) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF América | 16 | 11 | 2 | 3 | 36:16 | 20 | 35 |
| 2 |
|
CF Monterrey | 16 | 10 | 4 | 2 | 29:13 | 16 | 34 |
| 3 |
|
CF Pachuca | 16 | 9 | 4 | 3 | 28:15 | 13 | 31 |
| 4 |
|
Santos Laguna | 16 | 9 | 3 | 4 | 35:21 | 14 | 30 |
| 5 |
|
UANL Tigres | 16 | 8 | 3 | 5 | 21:14 | 7 | 27 |
| 6 |
|
Deportivo Toluca | 16 | 6 | 6 | 4 | 23:22 | 1 | 24 |
| 7 |
|
Puebla FC | 16 | 4 | 10 | 2 | 24:21 | 3 | 22 |
| 8 |
|
Deportivo Guadalajara | 16 | 5 | 7 | 4 | 18:15 | 3 | 22 |
| 9 |
|
Club León | 16 | 6 | 3 | 7 | 23:27 | -4 | 21 |
| 10 |
|
Cruz Azul | 16 | 6 | 3 | 7 | 24:33 | -9 | 21 |
| 11 |
|
Club Necaxa | 16 | 5 | 4 | 7 | 19:25 | -6 | 19 |
| 12 |
|
Atlético San Luis | 16 | 4 | 6 | 6 | 15:20 | -5 | 18 |
| 13 |
|
Mazatlán FC | 16 | 3 | 8 | 5 | 17:21 | -4 | 17 |
| 14 |
|
FC Juárez | 16 | 3 | 7 | 6 | 14:17 | -3 | 16 |
| 15 |
|
Club Tijuana | 16 | 4 | 4 | 8 | 16:28 | -12 | 16 |
| 16 |
|
Pumas UNAM | 16 | 2 | 8 | 6 | 20:28 | -8 | 14 |
| 17 |
|
Atlas Guadalajara | 16 | 2 | 4 | 10 | 15:27 | -12 | 10 |
| 18 |
|
Gallos Blancos | 16 | 1 | 6 | 9 | 17:31 | -14 | 9 |
| Playoff | |
| Playoff |
