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| 13.08.2022 | 16:00 | Deportivo Toluca | - | Cruz Azul | 3:3 (2:0) | |
| 16:00 | Pumas UNAM | - | CF América | 3:0 (2:0) | ||
| 16:00 | Santos Laguna | - | UANL Tigres | 1:0 (0:0) | ||
| 16:00 | Atlético San Luis | - | Deportivo Guadalajara | 0:0 (0:0) | ||
| 18:00 | CF Pachuca | - | FC Juárez | 1:3 (1:1) | ||
| 18:30 | Club Necaxa | - | Puebla FC | 6:2 (3:0) | ||
| 19:30 | Mazatlán FC | - | Club León | 2:1 (1:0) | ||
| 23:00 | CF Monterrey | - | Club Tijuana | 3:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Necaxa | 7 | 4 | 3 | 0 | 21:7 | 14 | 15 |
| 2 |
|
Pumas UNAM | 7 | 3 | 3 | 1 | 9:7 | 2 | 12 |
| 3 |
|
CF América | 7 | 3 | 2 | 2 | 13:12 | 1 | 11 |
| 4 |
|
CF Pachuca | 7 | 3 | 1 | 3 | 10:12 | -2 | 10 |
| 5 |
|
Cruz Azul | 7 | 2 | 3 | 2 | 15:12 | 3 | 9 |
| 6 |
|
FC Juárez | 8 | 2 | 3 | 3 | 9:12 | -3 | 9 |
| 7 |
|
Deportivo Toluca | 7 | 2 | 2 | 3 | 19:18 | 1 | 8 |
| 8 |
|
Gallos Blancos | 7 | 2 | 1 | 4 | 8:15 | -7 | 7 |
| 9 |
|
Puebla FC | 7 | 1 | 2 | 4 | 11:20 | -9 | 5 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Santos Laguna | 7 | 6 | 0 | 1 | 13:7 | 6 | 18 |
| 2 |
|
Mazatlán FC | 7 | 5 | 1 | 1 | 10:6 | 4 | 16 |
| 3 |
|
CF Monterrey | 8 | 5 | 0 | 3 | 17:10 | 7 | 15 |
| 4 |
|
Deportivo Guadalajara | 7 | 4 | 2 | 1 | 14:9 | 5 | 14 |
| 5 |
|
Atlético San Luis | 7 | 2 | 2 | 3 | 14:14 | 0 | 8 |
| 6 |
|
Club Tijuana | 7 | 2 | 2 | 3 | 7:9 | -2 | 8 |
| 7 |
|
Atlas Guadalajara | 7 | 2 | 1 | 4 | 6:9 | -3 | 7 |
| 8 |
|
UANL Tigres | 7 | 2 | 0 | 5 | 7:11 | -4 | 6 |
| 9 |
|
Club León | 7 | 0 | 0 | 7 | 5:18 | -13 | 0 |
| Playoff | |
| Playoff |
