 |
 |
|
|
| 16.04.2021 | 18:15 | Club Necaxa | - | Gallos Blancos | 5:0 (1:0) | |
| 17.04.2021 | 01:15 | Mazatlán FC | - | Atlas Guadalajara | 0:2 (0:0) | |
| 16:00 | CF América | - | Cruz Azul | 0:2 (0:1) | ||
| 18:15 | Deportivo Guadalajara | - | Club Tijuana | 1:1 (1:1) | ||
| 19:00 | Atlético San Luis | - | Puebla FC | 2:1 (0:1) | ||
| 18.04.2021 | 16:00 | Santos Laguna | - | Deportivo Toluca | 1:1 (0:1) | |
| 18:00 | Pumas UNAM | - | UANL Tigres | 4:0 (2:0) | ||
| 18:30 | CF Monterrey | - | CF Pachuca | 2:4 (0:4) | ||
| 19.04.2021 | 18:30 | Club León | - | FC Juárez | 4:0 (2:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 15 | 10 | 3 | 2 | 44:22 | 22 | 46 |
| 2 |
|
Atlas Guadalajara | 15 | 9 | 2 | 4 | 26:18 | 8 | 41 |
| 3 |
|
Club León | 15 | 9 | 4 | 2 | 29:16 | 13 | 38 |
| 4 |
|
Santos Laguna | 15 | 7 | 4 | 4 | 27:22 | 5 | 34 |
| 5 |
|
Deportivo Guadalajara | 15 | 7 | 5 | 3 | 27:17 | 10 | 33 |
| 6 |
|
UANL Tigres | 15 | 7 | 4 | 4 | 24:20 | 4 | 32 |
| 7 |
|
Club Tijuana | 15 | 7 | 2 | 6 | 24:22 | 2 | 32 |
| 8 |
|
Pumas UNAM | 15 | 7 | 2 | 6 | 24:18 | 6 | 31 |
| 9 |
|
Club Necaxa | 15 | 6 | 2 | 7 | 26:21 | 5 | 30 |
| 10 |
|
Cruz Azul | 15 | 7 | 1 | 7 | 24:24 | 0 | 30 |
| 11 |
|
Deportivo Toluca | 15 | 5 | 6 | 4 | 22:20 | 2 | 29 |
| 12 |
|
CF Monterrey | 15 | 6 | 2 | 7 | 23:23 | 0 | 27 |
| 13 |
|
FC Juárez | 15 | 6 | 1 | 8 | 19:21 | -2 | 26 |
| 14 |
|
Mazatlán FC | 15 | 4 | 4 | 7 | 16:27 | -11 | 26 |
| 15 |
|
Puebla FC | 15 | 5 | 3 | 7 | 23:26 | -3 | 25 |
| 16 |
|
Atlético San Luis | 15 | 2 | 2 | 11 | 13:40 | -27 | 20 |
| 17 |
|
Gallos Blancos | 15 | 3 | 2 | 10 | 17:33 | -16 | 17 |
| 18 |
|
CF América | 15 | 3 | 1 | 11 | 18:36 | -18 | 16 |
| Playoff |
