 |
 |
|
|
| 24.02.2022 | 16:00 | CF Pachuca | - | Mazatlán FC | 3:1 (2:0) | |
| 18:30 | Gallos Blancos | - | Deportivo Toluca | 0:2 (0:2) | ||
| 25.02.2022 | 18:15 | Club Necaxa | - | Club León | 2:0 (1:0) | |
| 19:30 | FC Juárez | - | UANL Tigres | 2:2 (0:0) | ||
| 21:45 | Club Tijuana | - | Atlas Guadalajara | 3:3 (1:2) | ||
| 26.02.2022 | 18:15 | Deportivo Guadalajara | - | Puebla FC | 3:0 (1:0) | |
| 18:30 | CF Monterrey | - | Atlético San Luis | 2:4 (1:1) | ||
| 18:30 | Pumas UNAM | - | CF América | 0:1 (0:1) | ||
| 27.02.2022 | 18:15 | Cruz Azul | - | Santos Laguna | 1:2 (0:2) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF América | 7 | 5 | 2 | 0 | 13:3 | 10 | 27 |
| 2 |
|
Atlas Guadalajara | 7 | 4 | 3 | 0 | 12:6 | 6 | 26 |
| 3 |
|
CF Monterrey | 7 | 4 | 1 | 2 | 13:12 | 1 | 24 |
| 4 |
|
Club Tijuana | 7 | 3 | 2 | 2 | 14:11 | 3 | 22 |
| 5 |
|
Deportivo Guadalajara | 7 | 4 | 1 | 2 | 15:8 | 7 | 21 |
| 6 |
|
Santos Laguna | 7 | 3 | 2 | 2 | 14:9 | 5 | 20 |
| 7 |
|
Deportivo Toluca | 7 | 3 | 3 | 1 | 12:7 | 5 | 20 |
| 8 |
|
Club León | 7 | 4 | 1 | 2 | 9:7 | 2 | 20 |
| 9 |
|
Cruz Azul | 7 | 3 | 1 | 3 | 8:8 | 0 | 19 |
| 10 |
|
UANL Tigres | 7 | 2 | 2 | 3 | 10:15 | -5 | 17 |
| 11 |
|
Atlético San Luis | 7 | 3 | 1 | 3 | 11:11 | 0 | 16 |
| 12 |
|
CF Pachuca | 7 | 3 | 0 | 4 | 10:12 | -2 | 16 |
| 13 |
|
Mazatlán FC | 7 | 1 | 2 | 4 | 6:15 | -9 | 15 |
| 14 |
|
Pumas UNAM | 7 | 2 | 1 | 4 | 7:12 | -5 | 14 |
| 15 |
|
FC Juárez | 7 | 1 | 3 | 3 | 10:11 | -1 | 13 |
| 16 |
|
Club Necaxa | 7 | 2 | 0 | 5 | 11:16 | -5 | 13 |
| 17 |
|
Gallos Blancos | 7 | 2 | 0 | 5 | 6:11 | -5 | 13 |
| 18 |
|
Puebla FC | 7 | 0 | 3 | 4 | 3:10 | -7 | 12 |
| Playoff |
