 |
 |
|
|
| 18.03.2021 | 19:00 | CF Pachuca | - | UANL Tigres | 2:1 (0:0) | |
| 19.03.2021 | 16:00 | Club Necaxa | - | FC Juárez | 2:4 (1:2) | |
| 17:00 | Mazatlán FC | - | CF América | 1:0 (1:0) | ||
| 20.03.2021 | 16:00 | CF Monterrey | - | Deportivo Guadalajara | 1:0 (0:0) | |
| 16:00 | Cruz Azul | - | Atlas Guadalajara | 0:4 (0:2) | ||
| 17:00 | Atlético San Luis | - | Pumas UNAM | 2:1 (0:1) | ||
| 23:45 | Club Tijuana | - | Gallos Blancos | 1:0 (0:0) | ||
| 21.03.2021 | 16:00 | Deportivo Toluca | - | Puebla FC | 1:2 (0:0) | |
| 18:00 | Santos Laguna | - | Club León | 3:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 12 | 8 | 3 | 1 | 24:11 | 13 | 27 |
| 2 |
|
CF Monterrey | 12 | 8 | 1 | 3 | 20:13 | 7 | 25 |
| 3 |
|
Mazatlán FC | 12 | 6 | 3 | 3 | 21:16 | 5 | 21 |
| 4 |
|
Deportivo Toluca | 12 | 6 | 2 | 4 | 22:16 | 6 | 20 |
| 5 |
|
Atlas Guadalajara | 12 | 6 | 2 | 4 | 16:11 | 5 | 20 |
| 6 |
|
Club León | 12 | 6 | 2 | 4 | 18:20 | -2 | 20 |
| 7 |
|
Santos Laguna | 12 | 5 | 4 | 3 | 20:10 | 10 | 19 |
| 8 |
|
Club Tijuana | 12 | 6 | 1 | 5 | 19:13 | 6 | 19 |
| 9 |
|
CF América | 12 | 5 | 3 | 4 | 19:11 | 8 | 18 |
| 10 |
|
FC Juárez | 12 | 5 | 3 | 4 | 13:15 | -2 | 18 |
| 11 |
|
UANL Tigres | 12 | 4 | 3 | 5 | 15:12 | 3 | 15 |
| 12 |
|
Pumas UNAM | 12 | 4 | 3 | 5 | 16:21 | -5 | 15 |
| 13 |
|
Puebla FC | 12 | 5 | 0 | 7 | 18:26 | -8 | 15 |
| 14 |
|
Atlético San Luis | 12 | 4 | 0 | 8 | 14:25 | -11 | 12 |
| 15 |
|
Cruz Azul | 12 | 3 | 3 | 6 | 9:20 | -11 | 12 |
| 16 |
|
Deportivo Guadalajara | 12 | 3 | 1 | 8 | 17:22 | -5 | 10 |
| 17 |
|
Gallos Blancos | 12 | 3 | 1 | 8 | 10:21 | -11 | 10 |
| 18 |
|
Club Necaxa | 12 | 2 | 3 | 7 | 11:19 | -8 | 9 |
| Playoff |
