 |
 |
|
|
| 11.03.2022 | 16:00 | Club Necaxa | - | Gallos Blancos | 2:1 (1:0) | |
| 16:00 | CF Monterrey | - | Mazatlán FC | 2:3 (1:1) | ||
| 20:30 | FC Juárez | - | Atlas Guadalajara | 0:0 (0:0) | ||
| 12.03.2022 | 16:00 | Club León | - | UANL Tigres | 2:1 (0:1) | |
| 16:00 | Cruz Azul | - | Pumas UNAM | 1:0 | ||
| 16:00 | Deportivo Guadalajara | - | CF América | 0:2 (0:0) | ||
| 18:00 | Santos Laguna | - | Club Tijuana | 4:2 (3:0) | ||
| 13.03.2022 | 16:00 | Deportivo Toluca | - | CF Pachuca | 1:1 (0:0) | |
| 16:00 | Atlético San Luis | - | Puebla FC | 3:1 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 10 | 7 | 1 | 2 | 21:12 | 9 | 22 |
| 2 |
|
Club León | 10 | 7 | 1 | 2 | 20:11 | 9 | 22 |
| 3 |
|
Atlético San Luis | 10 | 6 | 1 | 3 | 25:13 | 12 | 19 |
| 4 |
|
Club Tijuana | 10 | 6 | 1 | 3 | 16:13 | 3 | 19 |
| 5 |
|
Deportivo Toluca | 10 | 5 | 3 | 2 | 17:12 | 5 | 18 |
| 6 |
|
UANL Tigres | 10 | 5 | 2 | 3 | 19:12 | 7 | 17 |
| 7 |
|
Deportivo Guadalajara | 10 | 5 | 2 | 3 | 10:10 | 0 | 17 |
| 8 |
|
CF América | 10 | 5 | 1 | 4 | 17:10 | 7 | 16 |
| 9 |
|
Pumas UNAM | 10 | 4 | 3 | 3 | 11:8 | 3 | 15 |
| 10 |
|
Santos Laguna | 10 | 4 | 2 | 4 | 13:16 | -3 | 14 |
| 11 |
|
Cruz Azul | 10 | 3 | 4 | 3 | 11:9 | 2 | 13 |
| 12 |
|
Club Necaxa | 10 | 4 | 1 | 5 | 15:15 | 0 | 13 |
| 13 |
|
CF Monterrey | 10 | 3 | 3 | 4 | 12:18 | -6 | 12 |
| 14 |
|
Mazatlán FC | 10 | 3 | 1 | 6 | 11:18 | -7 | 10 |
| 15 |
|
Atlas Guadalajara | 10 | 2 | 3 | 5 | 7:14 | -7 | 9 |
| 16 |
|
Puebla FC | 10 | 2 | 1 | 7 | 11:23 | -12 | 7 |
| 17 |
|
FC Juárez | 10 | 1 | 3 | 6 | 8:21 | -13 | 6 |
| 18 |
|
Gallos Blancos | 10 | 0 | 3 | 7 | 2:11 | -9 | 3 |
| Playoff |
