17.12.2021 18:00 MFM FC - Remo Stars 0:2
19.12.2021 16:00 Gombe United - Shooting Stars 0:0
16:00 Akwa United - Kano Pillars 3:0
16:00 Lobi Stars - Rivers United 1:1
16:00 Enyimba Aba - Abia Warriors 2:1
16:00 Niger Tornadoes - Plateau United 1:0
16:00 Kwara United - Dakkada FC 3:0
16:00 Heartland FC - Nasarawa United 3:3
16:00 Katsina United - Enugu Rangers 1:2
20.12.2021 Sunshine Stars - Wikki Tourists apla.
# Equipo P V E D Goles DG Pun.
1 Akwa United, Nigeria Akwa United 1 1 0 0 3:0 3 3
  Kwara United, Nigeria Kwara United 1 1 0 0 3:0 3 3
3 Remo Stars, Nigeria Remo Stars 1 1 0 0 2:0 2 3
4 Enugu Rangers, Nigeria Enugu Rangers 1 1 0 0 2:1 1 3
  Enyimba Aba, Nigeria Enyimba Aba 1 1 0 0 2:1 1 3
6 Niger Tornadoes, Nigeria Niger Tornadoes 1 1 0 0 1:0 1 3
7 Heartland FC, Nigeria Heartland FC 1 0 1 0 3:3 0 1
  Nasarawa United, Nigeria Nasarawa United 1 0 1 0 3:3 0 1
9 Lobi Stars, Nigeria Lobi Stars 1 0 1 0 1:1 0 1
  Rivers United, Nigeria Rivers United 1 0 1 0 1:1 0 1
11 Gombe United, Nigeria Gombe United 1 0 1 0 0:0 0 1
  Shooting Stars, Nigeria Shooting Stars 1 0 1 0 0:0 0 1
13 Sunshine Stars, Nigeria Sunshine Stars 0 0 0 0 0:0 0 0
  Wikki Tourists, Nigeria Wikki Tourists 0 0 0 0 0:0 0 0
15 Abia Warriors, Nigeria Abia Warriors 1 0 0 1 1:2 -1 0
  Katsina United, Nigeria Katsina United 1 0 0 1 1:2 -1 0
17 Plateau United, Nigeria Plateau United 1 0 0 1 0:1 -1 0
18 MFM FC, Nigeria MFM FC 1 0 0 1 0:2 -2 0
19 Dakkada FC, Nigeria Dakkada FC 1 0 0 1 0:3 -3 0
  Kano Pillars, Nigeria Kano Pillars 1 0 0 1 0:3 -3 0
  Champions League
  Confederation Cup
  Descenso