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| 09.10.2021 | 02:00 | Deportivo del Este | - | Atlético Chiriquí | 1:0 (0:0) | |
| 02:00 | Alianza | - | Veraguas Club Deportivo | 0:1 (0:0) | ||
| 10.10.2021 | 00:00 | UD Universitario | - | Árabe Unido | 2:1 (0:1) | |
| 01:00 | Independiente de La Chorrera | - | Tauro FC | 1:0 (1:0) | ||
| 01:00 | Sporting San Miguelito | - | San Francisco FC | 1:1 (1:1) | ||
| 02:00 | Herrera FC | - | Plaza Amador | 0:2 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Tauro FC | 10 | 5 | 3 | 2 | 11:6 | 5 | 18 |
| 2 |
|
Alianza | 10 | 5 | 3 | 2 | 9:6 | 3 | 18 |
| 3 |
|
Plaza Amador | 10 | 3 | 5 | 2 | 8:5 | 3 | 14 |
| 4 |
|
Deportivo del Este | 10 | 2 | 7 | 1 | 10:8 | 2 | 13 |
| 5 |
|
Árabe Unido | 10 | 3 | 4 | 3 | 6:6 | 0 | 13 |
| 6 |
|
Sporting San Miguelito | 10 | 3 | 4 | 3 | 7:10 | -3 | 13 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Independiente de La Chorrera | 10 | 5 | 3 | 2 | 13:7 | 6 | 18 |
| 2 |
|
UD Universitario | 10 | 4 | 1 | 5 | 10:13 | -3 | 13 |
| 3 |
|
Herrera FC | 10 | 2 | 6 | 2 | 12:11 | 1 | 12 |
| 4 |
|
Veraguas Club Deportivo | 10 | 3 | 3 | 4 | 8:10 | -2 | 12 |
| 5 |
|
Atlético Chiriquí | 10 | 2 | 3 | 5 | 7:10 | -3 | 9 |
| 6 |
|
San Francisco FC | 10 | 0 | 4 | 6 | 5:14 | -9 | 4 |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff |
