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| 04.09.2021 | 02:00 | Deportivo del Este | - | Tauro FC | 1:2 (0:1) | |
| 02:00 | Herrera FC | - | UD Universitario | 1:2 (0:0) | ||
| 23:00 | Árabe Unido | - | Sporting San Miguelito | 0:1 (0:1) | ||
| 05.09.2021 | 01:00 | Alianza | - | Plaza Amador | 1:0 (0:0) | |
| 01:00 | Independiente de La Chorrera | - | Atlético Chiriquí | 1:2 (0:0) | ||
| 01:00 | Veraguas Club Deportivo | - | San Francisco FC | 1:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Alianza | 5 | 2 | 2 | 1 | 5:4 | 1 | 8 |
| 2 |
|
Sporting San Miguelito | 5 | 2 | 2 | 1 | 4:3 | 1 | 8 |
| 3 |
|
Tauro FC | 5 | 2 | 2 | 1 | 3:2 | 1 | 8 |
| 4 |
|
Árabe Unido | 5 | 2 | 1 | 2 | 3:3 | 0 | 7 |
| 5 |
|
Deportivo del Este | 5 | 0 | 4 | 1 | 4:5 | -1 | 4 |
| 6 |
|
Plaza Amador | 5 | 0 | 3 | 2 | 1:3 | -2 | 3 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
UD Universitario | 5 | 3 | 1 | 1 | 7:6 | 1 | 10 |
| 2 |
|
Atlético Chiriquí | 5 | 2 | 3 | 0 | 6:3 | 3 | 9 |
| 3 |
|
Independiente de La Chorrera | 5 | 3 | 0 | 2 | 8:6 | 2 | 9 |
| 4 |
|
Herrera FC | 5 | 2 | 2 | 1 | 8:5 | 3 | 8 |
| 5 |
|
Veraguas Club Deportivo | 5 | 1 | 1 | 3 | 3:6 | -3 | 4 |
| 6 |
|
San Francisco FC | 5 | 0 | 1 | 4 | 2:8 | -6 | 1 |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff |
