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| 02.04.2022 | 02:00 | San Francisco FC | - | Plaza Amador | 2:2 (1:2) | |
| 03:00 | Herrera FC | - | Deportivo del Este | 1:2 (1:2) | ||
| 23:00 | UD Universitario | - | Tauro FC | 0:1 (0:0) | ||
| 03.04.2022 | 01:00 | Independiente de La Chorrera | - | Alianza | 1:2 (1:1) | |
| 23:00 | Árabe Unido | - | Veraguas United | 0:0 (0:0) | ||
| 04.04.2022 | 01:00 | Sporting San Miguelito | - | Atlético Chiriquí | 4:1 (2:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Alianza | 10 | 6 | 3 | 1 | 10:3 | 7 | 21 |
| 2 |
|
Sporting San Miguelito | 10 | 5 | 5 | 0 | 16:8 | 8 | 20 |
| 3 |
|
Tauro FC | 10 | 4 | 3 | 3 | 11:8 | 3 | 15 |
| 4 |
|
Deportivo del Este | 10 | 2 | 6 | 2 | 11:11 | 0 | 12 |
| 5 |
|
Plaza Amador | 10 | 2 | 6 | 2 | 14:15 | -1 | 12 |
| 6 |
|
Árabe Unido | 10 | 0 | 6 | 4 | 2:6 | -4 | 6 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Chiriquí | 10 | 6 | 1 | 3 | 14:14 | 0 | 19 |
| 2 |
|
Independiente de La Chorrera | 10 | 5 | 2 | 3 | 11:8 | 3 | 17 |
| 3 |
|
Herrera FC | 10 | 2 | 6 | 2 | 10:9 | 1 | 12 |
| 4 |
|
Veraguas United | 10 | 1 | 5 | 4 | 8:14 | -6 | 8 |
| 5 |
|
UD Universitario | 10 | 2 | 2 | 6 | 6:13 | -7 | 8 |
| 6 |
|
San Francisco FC | 10 | 1 | 3 | 6 | 6:10 | -4 | 6 |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff |
