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| 26.02.2022 | 02:00 | San Francisco FC | - | UD Universitario | 0:1 (0:0) | |
| 22:00 | Deportivo del Este | - | Tauro FC | 0:2 (0:2) | ||
| 27.02.2022 | 00:00 | Plaza Amador | - | Árabe Unido | 2:2 (1:1) | |
| 02:00 | Veraguas United | - | Independiente de La Chorrera | 1:1 (0:0) | ||
| 22:00 | Alianza | - | Sporting San Miguelito | 0:1 (0:0) | ||
| 28.02.2022 | 00:00 | Herrera FC | - | Atlético Chiriquí | 1:2 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Tauro FC | 4 | 2 | 1 | 1 | 8:5 | 3 | 7 |
| 2 |
|
Alianza | 4 | 2 | 1 | 1 | 2:1 | 1 | 7 |
| 3 |
|
Sporting San Miguelito | 4 | 1 | 3 | 0 | 5:4 | 1 | 6 |
| 4 |
|
Plaza Amador | 4 | 1 | 2 | 1 | 8:9 | -1 | 5 |
| 5 |
|
Árabe Unido | 4 | 0 | 3 | 1 | 2:3 | -1 | 3 |
| 6 |
|
Deportivo del Este | 4 | 0 | 2 | 2 | 3:6 | -3 | 2 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Chiriquí | 4 | 3 | 0 | 1 | 5:5 | 0 | 9 |
| 2 |
|
Herrera FC | 4 | 2 | 1 | 1 | 7:5 | 2 | 7 |
| 3 |
|
UD Universitario | 4 | 1 | 2 | 1 | 5:5 | 0 | 5 |
| 4 |
|
Veraguas United | 4 | 1 | 2 | 1 | 4:5 | -1 | 5 |
| 5 |
|
Independiente de La Chorrera | 4 | 1 | 1 | 2 | 5:5 | 0 | 4 |
| 6 |
|
San Francisco FC | 4 | 1 | 0 | 3 | 3:4 | -1 | 3 |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff |
