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| 08.04.2022 | 17:00 | Tatran Liptovský Mikuláš | - | MFK Zemplín Michalovce | 3:1 (2:0) | |
| 09.04.2022 | 18:00 | FK Senica | - | FK Pohronie | 2:1 (0:0) | |
| 26.04.2022 | 18:00 | AS Trenčín | - | Zlaté Moravce | 4:3 (2:1) |
| » Clasificación | En casa | Fuera de casa |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
AS Trenčín | 27 | 10 | 7 | 10 | 45:38 | 7 | 37 |
| 2 |
|
FK Senica | 27 | 9 | 6 | 12 | 29:43 | -14 | 33 |
| 3 |
|
MFK Zemplín Michalovce | 27 | 10 | 2 | 15 | 25:36 | -11 | 32 |
| 4 |
|
Tatran Liptovský Mikuláš | 27 | 8 | 7 | 12 | 34:49 | -15 | 31 |
| 5 |
|
Zlaté Moravce | 27 | 6 | 7 | 14 | 29:44 | -15 | 25 |
| 6 |
|
FK Pohronie | 27 | 2 | 5 | 20 | 21:54 | -33 | 11 |
| Playoff | |
| Descenso |
