01.10.2021 13:00 Chonburi FC - Chiangrai United 2:3 (2:1)
02.10.2021 12:00 Port FC - Muangthong United 1:0 (1:0)
13:00 PT Prachuap FC - Buriram United 0:2 (0:1)
13:00 Samut Prakan City FC - Chiangmai FC 1:3 (0:0)
14:00 Nong Bua Pitchaya - Police Tero FC 1:0 (1:0)
03.10.2021 13:00 Nakhon Ratchasima - Suphanburi FC 2:1 (0:1)
13:00 BG Pathum United - Khonkaen FC 2:1 (2:0)
20.10.2021 13:00 Ratchaburi Mitr Phol - Bangkok United 1:2 (0:0)
# Equipo P V E D Goles DG Pun.
1 Buriram United, Tailandia Buriram United 5 3 1 1 9:3 6 10
2 Bangkok United, Tailandia Bangkok United 5 3 1 1 8:6 2 10
  BG Pathum United, Tailandia BG Pathum United 5 3 1 1 8:6 2 10
4 Nong Bua Pitchaya, Tailandia Nong Bua Pitchaya 5 3 0 2 7:5 2 9
5 Chonburi FC, Tailandia Chonburi FC 5 2 2 1 16:8 8 8
6 Chiangrai United, Tailandia Chiangrai United 5 2 2 1 9:8 1 8
7 Port FC, Tailandia Port FC 5 2 2 1 8:7 1 8
  Samut Prakan City FC, Tailandia Samut Prakan City FC 5 2 2 1 8:7 1 8
9 Nakhon Ratchasima, Tailandia Nakhon Ratchasima 5 2 1 2 6:7 -1 7
10 Suphanburi FC, Tailandia Suphanburi FC 5 1 3 1 8:7 1 6
11 Muangthong United, Tailandia Muangthong United 5 1 2 2 8:9 -1 5
12 PT Prachuap FC, Tailandia PT Prachuap FC 5 1 2 2 7:9 -2 5
13 Chiangmai FC, Tailandia Chiangmai FC 5 1 2 2 7:10 -3 5
14 Ratchaburi Mitr Phol, Tailandia Ratchaburi Mitr Phol 5 1 1 3 4:6 -2 4
15 Khonkaen FC, Tailandia Khonkaen FC 5 1 0 4 3:14 -11 3
16 Police Tero FC, Tailandia Police Tero FC 5 0 2 3 5:9 -4 2
  Champions League
  CL Ronda previa
  Descenso